SORT1 polyclonal antibody
产品名称： SORT1 polyclonal antibody
英文名称： SORT1 polyclonal antibody
产品编号： PAB0734
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against partial recombinant SORT1.
- Immunogen:
- Recombinant protein corresponding to extracellular region of human SORT1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Lyophilized
- Storage Buffer:
- Lyophilized from PBS
- Storage Instruction:
- Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.
- Applications
- Immunohistochemistry (Frozen sections)
- IHC on rat spinal cord (free floating cryo section) using rabbit SORT1 polyclonal antibody (Cat # PAB0734) at a dilution of 1 : 1000.
- Immunohistochemistry (Frozen sections)
- IHC on rat DRG (free floating cryo section) using rabbit SORT1 polyclonal antibody (Cat # PAB0734) at a dilution of 1 : 1000.
- Entrez GeneID:
- 6272
- Protein Accession#:
- Q99523
- Gene Name:
- SORT1
- Gene Alias:
- Gp95,NT3
- Gene Description:
- sortilin 1
- Omim ID:
- 602458
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq
- Other Designations:
- OTTHUMP00000013784,neurotensin receptor 3
- Gene Pathway